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ADHD Medication During Pregnancy and Breastfeeding

Women suffering from ADHD have to make a difficult choice on whether to keep or stop taking ADHD medication during pregnancy and breast-feeding. There isn't much information on how long-term exposure to these drugs may affect the fetus.

A study recently published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological issues such as impaired hearing or vision, febrile seizures, or IQ impairment. The authors acknowledge the need for more high-quality research.

Risk/Benefit Analysis

Pregnant women who use ADHD medications need to balance the advantages of taking them against potential risks to the fetus. Doctors don't have the data needed to make unequivocal recommendations, but they can provide information regarding the risks and benefits to aid pregnant women in making informed decisions.

A study published in Molecular Psychiatry found that women who were taking adhd without medication medications in early pregnancy did not have a significantly increased risk of fetal heart malformations or major structural birth defects. The researchers used a large population-based study of case-control to evaluate the incidence of major structural birth defects in babies born to mothers who had taken stimulants in early pregnancy, as well as those who had not. Clinical geneticists and pediatric cardiologists reviewed the cases to ensure correct classification of the cases and to reduce the chance of bias.

human-givens-institute-logo.pngThe study conducted by the researchers was not without its limitations. In particular, they were unable to distinguish the effects of the medication from the effects of the disorder at hand. That limitation makes it difficult to determine whether the small associations observed in the exposed groups are due to medication use or confounding by comorbidities. Researchers also did not look at long-term outcomes for the offspring.

The study did find that infants whose mothers took ADHD medication during pregnancy were at a slightly greater risk of being admitted to the neonatal intensive care unit (NICU) than infants who whose mothers did not take any medication or taken off their medication prior to or during pregnancy. This increase was due to central nervous system-related disorders and the increased risk of admission was not found to be affected by the type of stimulant medications were taken during pregnancy.

Women who took stimulant adhd stimulant medication medication during pregnancy were also at an increased chance of having a caesarean birth or having a baby born with low Apgar score (less than 7). These increases did appear to be independent of the type of medication taken during pregnancy.

The researchers suggest that the risk of a small amount with the use of ADHD medications during the early stages of pregnancy could be offset by the greater benefit to both the mother and child of continuing treatment for the woman's disorder. Physicians should discuss the issue with their patients and, when they are able, assist them in developing strategies to improve their coping abilities that can lessen the negative impact of her condition on her daily functioning and relationships.

Medication Interactions

Doctors are increasingly confronted with the dilemma of whether to keep treatment or stop it during pregnancy as more women are diagnosed with ADHD. The majority of these decisions are taken in the absence of any evidence that is clear and definitive either way, so physicians must weigh what they know, the experiences of other doctors, and what the research suggests about the subject as well as their own judgments for each individual patient.

The issue of potential risks to infants is extremely difficult. The research that has been conducted on this topic is based on observations rather than controlled studies, and a lot of the results are conflicting. Furthermore, most popular adhd medication (marvelvsdc.faith blog article) studies restrict their analysis to live births, which may underestimate severe teratogenic effects that cause abortion or termination of the pregnancy. The study that is discussed in this journal club addresses these shortcomings by examining data on both live and deceased births.

The conclusion The conclusion: While certain studies have demonstrated an association between ADHD medications and the possibility of certain birth defects, others have found no connection, and most studies demonstrate a neutral or slightly negative impact. In the end an accurate risk-benefit analysis is required in every instance.

For women suffering from ADHD who suffer from adhd depression medication, the decision to discontinue medication is difficult, if not impossible. In a recent article in the Archives of Women's Mental Health, psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can cause depression, feelings of loneliness and family conflict for those suffering from the disorder. A decrease in medication could also impact the ability to safely drive and to perform work-related tasks which are crucial aspects of everyday life for those with ADHD.

She suggests that women who are unsure about whether to continue or discontinue medication due to their pregnancy consider the possibility of educating friends, family members, and coworkers on the condition, its impact on daily life, and the benefits of keeping the current treatment plan. In addition, educating them can help the woman feel supported in her struggle with her decision. It is important to note that certain medications are able to pass through the placenta, so if the patient decides to stop taking her ADHD medication during pregnancy and breastfeeding, she must be aware that the effects of the medication could be transferred to the infant.

Risk of Birth Defects

As the use and misuse of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD), increases as does the concern about the possible effects of the drugs on fetuses. A study that was published in the journal Molecular Psychiatry adds to the body of knowledge about this subject. Researchers used two huge datasets to analyze over 4.3 million pregnant women and determine whether stimulant medications increased birth defects. Researchers found that while the risk overall is low, first-trimester ADHD medication exposure was associated with slightly higher rates of certain heart defects, such as ventriculoseptal defect.

The authors of the study could not find any association between early use of medication and congenital anomalies like facial deformities or club feet. The results are in agreement with previous studies which showed a small, but significant increase in cardiac malformations for women who began taking ADHD medication before the time of pregnancy. The risk increased in the latter part of pregnancy, when a lot of women stopped taking their medication.

Women who used ADHD medications during the first trimester of their pregnancies were also more likely to undergo a caesarean section, a low Apgar score after delivery and a baby who needed breathing assistance during birth. However, the authors of the study were not able to eliminate selection bias by restricting the study to women who didn't have other medical issues that could have contributed to the findings.

general-medical-council-logo.pngResearchers hope that their research will help doctors when they see pregnant women. The researchers suggest that while discussing risks and benefits are important, the decision regarding whether or not to stop medication should be made in light of the severity of each woman's ADHD symptoms and her requirements.

The authors warn that, even though stopping the medication is a possibility to look into, it is not advised due to the high prevalence of depression and mental health issues among women who are pregnant or who have recently given birth. Additionally, research suggests that women who stop taking their medications will have a harder adjustment to life without them once the baby is born.

Nursing

The responsibilities that come with being a new mom can be overwhelming. Women suffering from ADHD can face severe challenges when they must manage their symptoms, attend doctor appointments and prepare for the birth of a child and adjust to a new routine. Many women opt to continue taking their ADHD medication during pregnancy.

The risk to a nursing infant is low because the majority of stimulant medications is absorbed through breast milk at low levels. The rate of medication exposure will differ based on dosage, frequency of administration and the time of day. In addition, different medications are introduced into the baby's system through the gastrointestinal tract or through breast milk. The effect on the health of a newborn isn't completely comprehended.

Due to the absence of research, some doctors may be inclined to discontinue stimulant medication during a woman's pregnancy. It's a difficult choice for the woman, who must weigh the benefits of continuing her medication against the risks to the foetus. In the meantime, until more information is available, GPs can ask pregnant patients if they have an history of ADHD or if they are planning to take medication in the perinatal period.

Many studies have shown that women can continue to take their ADHD medication without risk while breastfeeding and during pregnancy. In response, a growing number of patients are choosing to continue their medication. They have concluded after consulting with their physicians, that the benefits of keeping their current medication outweigh possible risks.

It is essential for women with ADHD who are considering breastfeeding to seek a specialist psychiatrist's advice prior becoming pregnant. They should discuss their medication given for adhd with their physician and discuss the pros and cons of continued treatment, including non-pharmacological strategies. Psychoeducation is also needed to help pregnant women suffering from ADHD be aware of the symptoms and the underlying disorder. They should also learn about treatment options and strengthen strategies for coping. This should be a multidisciplinary approach with the GP as well as obstetricians, psychiatry and obstetricians. Pregnancy counseling should include discussion of a treatment plan for the mother and child, monitoring of indicators of deterioration, and, if needed adjustments to the medication regime.

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